ASSESSING THE CO-RELATION BETWEEN MANDIBULAR FLARE AND THICKNESS OF LINGUAL CORTEX IN RELATION TO THE THIRD MOLARS: A RETROSPECTIVE CROSS-SECTIONAL STUDY

Aim: To assess the co-relation between mandibular flare and thickness of lingual cortex in relation to the third molars.Materials and Methods: Retrospectively obtained computed tomography (CT) data of 26 patients was used after classifying them into respective skeletal malocclusion groups (classes I, II, and III).Thickness of lingual cortex was mea

Immune checkpoint blockade (ICB) has changed the therapeutic landscape of oncology but its impact is limited by primary or secondary resistance.ICB resistance has been related to a lack of T cells infiltrating into the tumor.Strategies to overcome this hurdle have so far focused on the tumor microenvironment, but have mostly overlooked the role of

Background & aims: Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid.We aimed to evaluate the effectiveness and safety of OCA under real-world conditions.Methods: Patients were recruited into the Italian PBC Registry,

ABSTRACT: Dendritic cells have attracted great interest from researchers as they may be used as targets of tumor immune evasion mechanisms.The main objective of this study was to evaluate the relationship between the dendritic cells (DCs) subpopulation in simple type mammary carcinomas in female dogs.Two groups of samples were used: the control gro